Métodos de Investigação em Neuropatologia
Programa de Pós-Graduação Stricto Sensu em Patologia Ambiental e Experimental
- Ementa:
- Estudo das bases etiopatogênicas das principais doenças do sistema nervoso (neurodegenerativas e desmielinizantes), bem como dos modelos e métodos de investigação utilizados na pesquisa em neuropatologia.
- Bibliografia:
- COSTA, V. G. C.; ARAÚJO, S. E. S.; ALVES-LEON, S. V.; GOMES, F. C. A. Central nervous system demyelinating diseases: glial cells at the hub of pathology. Frontiers in Immunology, v. 14, p. 1–20, 2023.
- D’ASCENZO, M.; COLUSSI, C. Oxidative stress and the central nervous system. Antioxidants, v. 14, p. 110, 2025.
- DEMMINGS, A. D. et al. (Re)Building the nervous system: a review of neuron-glia interactions from development to disease. Journal of Neurochemistry, v. 169, e16258, 2025.
- ESCALADA, P.; EZKURDIA, A.; RAMIREZ, M. J.; SOLAS, M. Essential role of astrocytes in learning and memory. International Journal of Molecular Sciences, v. 25, p. 1899, 2024.
- GIOVANNONI, F.; QUINTANA, F. J. The role of astrocytes in CNS inflammation. Trends in Immunology, v. 41, p. 805–819, 2020.
- LAMPTEY, R. N. L.; CHAULAGAIN, B.; TRIVEDI, R.; GOTHWAL, A.; LAYEK, B.; SINGH, J. A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics. International Journal of Molecular Sciences, v. 23, p. 1851, 2023.
- RAO, V.; BHUSHAN, R.; KUMARI, P.; CHERUKU, S. P.; RAVICHANDIRAN, V.; KUMAR, N. Chapter Two - Chemobrain: a review on mechanistic insight, targets and treatments. Advances in Cancer Research, v. 155, p. 29–76, 2022.
- RUPARELIYA, V. P.; SINGH, A. A.; BUTT, A. M.; HARIHARAN, A.; KUMAR, H. The “molecular soldiers” of the CNS: astrocytes, a comprehensive review on their roles and molecular signatures. European Journal of Pharmacology, v. 959, p. 176048, 2023.